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SHORT-TERM SIDE EFFECTS
SHORT-TERM SIDE EFFECTS

SHORT-TERM
SIDE
EFFECTS

Understanding Short-Term Side Effects of Prostate Radiation Therapy

Modern radiation technology uses advanced techniques to accurately target tumors.1 However, like many medical treatments, it can cause short-term (acute) side effects.2,3

Side effects can vary depending on the individual, type of treatment, and other factors. Talk to your doctor about what to expect and how to manage any symptoms.

Possible Short-Term Side Effects**

Some short-term side effects of radiation therapy for prostate cancer may include:1


Radiation cystitis - bladder irritation that can cause symptoms like:

  • Urinating more frequently

  • Urgent need or stronger sensation to urinate

  • Burning sensation with urination

  • Blood in the urine


Radiation proctitis - irritation of the rectal lining that can cause symptoms like:

  • Diarrhea

  • Blood in the stool
  • Hemorrhoids
  • Rectal leakage

Sexual side effects3,4

  • Erectile dysfunction

  • Decreased libido


Potential Impact of Short-term Side Effects3

Short-term side effects can cause temporary discomfort and impact daily life. If symptoms become moderate to severe, treatment may be delayed. Some short-term side effects can also increase the risk of developing long-term complications.

**NOTE: These are examples. It is important to consult with your doctor about all potential side effects you may experience during and after treatment.

 

Reducing Rectal Side Effects from Prostate Radiation Therapy

Because the rectum is close to the prostate, it is at risk for side effects during prostate radiation therapy. The use of Barrigel™ spacer can reduce rectal side effects by temporarily positioning the rectum away from the prostate during radiation treatment.5

References

  • 1.    American Cancer Society. Radiation Therapy for Prostate Cancer. Accessed April 2025. https:/lwww.cancer.org/cancer/prostate­ cancer/treatlng/radiatlon-therapy.html
    2.    Mayo Clinic. Radiation Therapy. www.mayoclinic.org. Accessed: April 29, 2025. https://www.Mayoclinic.org/tests-procedures/radiation-therapy/about/pae-20385162
    3.    Oncolink. Possible Side Effects of Radiation Treatment for Prostate Cancer. Abramson Cancer Center, University of Pennsylvania. https://www.oncolink.org/cancers/prostate/treatments/possible-side-effects-0f-radiation-treatment-for-prostate-cancer
    4.    Healthline. Side Effects of Radiation for Prostate Cancer. Apr 2025; https://www.healthline.com/health/prostate-cancer/side-effects-of-radiation-for-prostate-cancer
    5.    Mariados NF, Orio PF Ill, King Met al. JAMA Oncol (2023)*
    * study sponsored by Palette Life Sciences, now part of Teleflex

APM1226-05A