Control Matters | Barrigel for Healthcare Providers

ANNOUNCEMENT: Teleflex has entered into a definitive agreement to divest our Interventional Urology portfolio, including the UroLift System™, Barrigel™ rectal spacer, Deflux™ injectable gel, and Solesta™ bulking agent, to Intersurgical^®. This transaction is expected to close in the second half of 2026, subject to customary regulatory approvals and other closing conditions. We’re excited about this opportunity and remain committed to providing the same high-quality products, reliable service, and on-time delivery our customers expect. We will keep our physicians and patients informed throughout the transition. Please feel free to contact your sales representative with any questions or concerns.

Controlled Spacing with Barrigel Rectal Spacer What is controlled spacing in prostate cancer radiation therapy? The ability to create safe, anatomically-customized spacing for radiotherapy patients.1,2 Inherent Qualities: controllable sculptable flexible Controllable Barrigel rectal spacer gives you the ability to: Refine and adjust placement.1-4 in real-time.3,7 Sculptable Barrigel rectal spacer is sculptable, allowing customization throughout the procedure.1-3,5 Intentional Placement Barrigel rectal spacer allows for intentional placement, providing control over implant shape and placement.1-3,5 Controlled Spacing Results from the Barrigel Pivotal Trial.1 98.5% of patients achieved an average 85% dose reduction to the rectum (rV54) 20% of patients achieved 100% dose reduction to the rectum (rV54) Barrigel spacer was proven superior in the reduction of acute grade 2+ GI toxicity compared to control Zero (0) reports of implant migration For full study results please visit Barrigel.com IN RECTAL SPACING CONTROL MATTERS. References: Mariados NF, Orio PF III, King MT et al. JAMA Oncol (2023).*§ Svatos M, Chell E, Low DA et al. Med Phys (2024).*§ Gejerman G, Goldstein MM, Chao M et al. Pract Radiat Oncol (2023).§ Barrigel Injectable Gel Instructions for Use (2022). Williams J, Mc Millan K, Chao M et al. J Med Imaging Radiat Sci (2022).§ * Study sponsored by Palette Life Sciences, now part of Teleflex. § One or more of the authors are paid consultants of Teleflex.

Hear from BARRIGEL PHYSICIANS*

“I have found that Barrigel spacer removes the element of uncertainty from rectal spacing. It allows me to carefully plan and adjust the placement of the gel and provide my patients with the best chance to eliminate rectal toxicity. It has already made a huge difference to my prostate cancer patients!”

– Suraj Singh, MD, Radiation Oncologist, Director at Parkview Comprehensive Cancer Center

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Hear from BARRIGEL PHYSICIANS*

“In my experience, Barrigel spacer is safer due to the ability to control its location and alter its placement during the procedure. This allows us to have a more uniform result in tougher cases where another procedure could result in delay of care.”

– Varun Sundaram, MD, Urologist, Urology Austin

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*This information reflects the personal experiences and professional medical opinions of the featured healthcare providers. Results may vary. All featured physicians are paid consultants of Teleflex.

References

1. Mariados NF, Orio PF III, King MT et al. JAMA Oncol (2023).^†§
2. Svatos M, Chell E, King MT et al. Med Phys (2024).^†§
3. Williams J, Mc Millan K, Chao M et al. J Med Imag Radiat Sci (2022).^§
4. Gejerman G, Goldstein MM, Chao M et al. Pract Radiat Oncol (2023).^§
5. Data on file. As of 4/01/2025.
† Study sponsored by Palette Life Sciences, now part of Teleflex.
§ One or more of the authors are paid consultants of Teleflex.