Let’s Get
PERSONAL
Enhance your prostate radiation treatment plan with the only rectal spacer that can be tailored to your anatomy.1-5
We call it personalized spacing.
If you or someone you love has recently been diagnosed with prostate cancer,
we know you have important decisions to make regarding your treatment plan. There are several treatment options available, including radiation therapy.
Many men select and receive radiation as a part of their prostate cancer treatment.6,8
But there are potential side effects. Radiation beams can negatively affect healthy tissue nearby, which can result in short and long-term side effects.
Due to its close proximity
to the prostate, the rectum is most at risk for radiation exposure.
WHY IT MATTERS
WHY IT MATTERS
Rectal swelling
Pain
Hemorrhoids
Diarrhea
PROTECT AGAINST
POTENTIAL SIDE EFFECTS
PROTECTION AGAINST POTENTIAL SIDE
EFFECTS
BarrigelTM Hyaluronic Acid Rectal Spacer
protects the rectum by moving it away from the high dose radiation field prior to radiation therapy. As a result, Barrigel™spacer has been proven to significantly reduce rectal side effects in a clinical trial.1
I like to use Barrigel on the vast majority of my radiation patients. Whenever we're doing radiation, the key is to be as precise as possible to eradicate the cancer. And the concept of putting a perirectal spacer is, clearly one of the best, advancements we've had in recent years in terms of treating the prostate. When we're putting in a perirectal spacer, the goal is always to, create as much space as possible between the rectum and the prostate, without compressing the prostate, but also having it as symmetrical as possible. Varijo can be used for patients who have larger prostates, smaller prostates. It's not a one size fits all. There is an advantage to being able to put as much or as little as we would wanna put while creating that space between the prostate and the rectum. One advantage of sculpting, is that we can go back and look at different parts of the prostate, to make sure that there's enough distance between the prostate and the rectum at that particular area. So for example, for the base to the apex, from right to left, we wanna make sure, that there's, adequate space, for the entire volume, of the prostate. And definitely, Barrigel allows you to do that in an extremely confident manner because you can see where you put the Barrigel and you're able to achieve that sparing of the rectum. Spacing has resulted in an extremely low chance of any rectal toxicity. So I'm fielding less phone calls. I'm having patients with less complications. Every radiation patient would benefit from, perirectal spacer like Barrigel .
PERSONALIZED PROTECTION
WITH BARRIGELTM SPACER1,10
PERSONALIZED PROTECTION
WITH BARRIGELTM SPACER1,10
Barrigel™ rectal spacer gives the physician control over the shape and placement of the implant.1-4 The result is an implant personalized to the unique contours of your anatomy.1-4
Minimize the side effects of prostate radiation therapy with Barrigel. Radiation therapy for the treatment of prostate cancer uses high energy beams to destroy and stop the spread of cancer cells. These high energy beams can negatively affect healthy tissues surrounding the prostate. Due to its close proximity to the prostate, the rectum is most at risk for radiation exposure. Barrigel Rectal Spacer can help minimize prostate radiation side effects by temporarily positioning the rectum away from the prostate. By creating space between the prostate and the rectum, Barrigel moves the healthy organ out of radiation beam exposure. Let's look at how Barrigel works. In rectal spacing, achieving complete and even coverage of the healthy tissue surrounding the prostate is crucial for protection from unwanted radiation exposure. The more even and consistent the rectal spacer, the more protection it provides the healthy tissue. Barrigel remains soft and pliable during insertion, your doctor to sculpt the spacer in place. The result is a custom implant tailored to your anatomy, offering more personalised coverage for more complete protection. Barrigel remains in place throughout the course of your radiation treatment, maintaining the space between your prostate and rectum until it is safely absorbed by your body. The seminal vesicles, which produce seminal fluid, are often exposed to radiation when treating prostate cancer. Protecting the rectum from seminal vesicle radiation exposure can help further reduce potential side effects. Barrigel is made from non animal stabilised hyaluronic acid known as NASHA. Hyaluronic acid is a substance naturally present in the human body and is highly and fully absorbable by the body. NASHA has been used for over two decades in more than fifty million procedures in men, women and children worldwide. To learn more about the benefits of Barrigel Rectal Spacer, visit barrigel.com.
CLINICALLY
PROVEN1
CLINICALLY
PROVEN1
SAFETY AND
STABILITY1
SAFETY AND
STABILITY1
* Data from the Barrigel Pivotal Study analyzed using the same methodology as the Fischer-Valuck study.
References
1. Mariados NF, Orio PF Ill, Schiffman Z et al. Hyaluronic acid spacer for hypofractionated prostate radiation therapy: A randomized clinical trial. JAMA Oncol. 2023: e1-e8.*
2. Svatos M, Chell E, Low DA et al. Med Phys (2024).*
3. Gejerman G, Goldstein MM, Chao M et al. Pract Radial Oncol (2023).**
4. Williams J, Mc Millan K, Chao Met al. J Med Imag Radial Sci (2022).
5. Data on file. As of 4/1/25.
6. American Cancer Society. Prostate Cancer. www.cancer.org: Accessed 7/8/25
7. Atun R, Jaffray DA, Barton MB et al, Lancet Oncol (2015).
8. Pienta KJ, Gorin MA, Rowe SP et al, J Urol (2021).
9. Oncolink. Possible Side Effects of Radiation Treatment for Prostate Cancer. Abramson Cancer Center, University of Pennsylvania. Apr2025; https://www.oncolink.org/cancers/prostate/treatments/possible-side-effects-of-radiation-treatment-for-prostate-cancer
10. King MT, Svatos M, Orio PF III et al. Pract Radiat Oncol (2023).*
*Study sponsored by Palette Life Sciences, now part of Teleflex
**Drs. Geierman, Chao, Lederer, and Orio are paid consultants of Palette Life Sciences, now part of Teleflex.
†Dr. Mehta is a paid consultant of Teleflex
