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How
Barrigel™

Rectal Spacer
Works

Significantly reduce rectal side effects of prostate radiation therapy with CLINICALLY PROVEN1 Barrigel™ rectal spacer.

The Importance of Space

Being located so close to the prostate puts the rectum at risk for radiation exposure.

Radiation-Dose-Margin-Without-Barrigel

Prostate cancer radiation therapy without a rectal spacer

Radiation Dose Margin Illustration FNL

Prostate cancer radiation therapy with Barrigel™ rectal spacer

Barrigel™ rectal spacer helps protect the rectum by reducing the amount of high-dose radiation that reaches it during treatment.1

How it Works

Barrigel™ rectal spacer is a biocompatible hyaluronic gel, placed between the prostate and rectum before radiation therapy starts.2-3,† The space created helps protect the rectum by moving it out of the high-dose radiation area.1

The spacer stays in place for the duration of your radiation therapy,1,2 and your body safely aborbs the gel over time.2,3

See how Barrigel™ works to protect healthy rectal tissue from unwanted high-dose radiation exposure.

PERSONALIZED SPACING FOR OPTIMAL COVERAGE

Barrigel protecting rectum during prostate radiation

Barrigel™ spacer is the only rectal spacer that can be sculpted to fit the unique contours of your anatomy.1,2,4-6 This advanced control helps your doctor create an even, consistent implant that provides optimal coverage1,2,5 between the prostate and rectum.

SAFE AND EFFECTIVE

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To date, Barrigel™ spacer has been used in over 60,000†† cancer patients during prostate radiation therapy. Barrigel™ rectal spacer is made from Non-Animal Stabilized Hyaluronic Acid also known as NASHA.7

The NASHA Platform has a proven history of safety and efficacy and is used in many common medical procedures worldwide.†,2,3

NASHA slide-simplified

References

  • 1. Mariados NF, Orio PF III, King MT et al. JAMA Oncol (2023).*
    2. Svatos M, Chell E, Low DA et al. Med Phys (2024)*
    3. Restylane® celebrates 25 years of natural-looking results with its signature line of hyaluronic acid fillers. 2021
    4. Williams J, Mc Millan K, Chao M et al. J Med Imag Radiat Sci (2022).
    5. Gejerman G, Goldstein MM, Chao M et al. Pract Radiat Oncol (2023).**
    6. Data on File. As of 4/01/2025.
    7. Barrigel Injectable Gel Instructions for Use (2022).
    8. King MT, Svatos M, Orio PF III et al. Pract Radiat Oncol (2023).*
    *Study sponsored by Palette Life Sciences, now part of Teleflex.
    **Drs Gejerman, Chao, Lederer, and Orio are paid consultants of Palette Life Sciences, now part of Teleflex.
    †Barrigel, made from NASHA, is indicated for rectal spacing in prostate cancer patients and was FDA-cleared in May, 2022.
    ††Management estimate based on product sales as of January 2025
APM1226-10A