
Are you aware of potential rectal side effects from prostate radiation?
If you’re undergoing radiation therapy for prostate cancer, you may be concerned about potential side effects like diarrhea, rectal bleeding, and hemorrhoids.
Barrigel™ spacer is the only rectal spacer that can be tailored to your unique anatomy,1,2,6 protecting the rectum by moving it out of the high-dose radiation area.1
The rectum is at risk for RADIATION EXPOSURE.
Many men with prostate cancer receive radiation therapy3 – however, radiation beams can potentially affect healthy tissue near the prostate and result in long-term radiation side effects. Due to its close proximity to the prostate, the rectum is at risk for radiation beam exposure.
Barrigel™ spacer helps protect the rectum by reducing the amount of radiation that reaches it during treatment.1

When I found out I had the elevated levels of PSA, I just decided, you know, just get the test done, see what the results are going to be, and just go on down the road. Cancer. Doctor Sundaram is the urologist that I went to. Very thorough, very friendly guy. He explained to me what all of the different options were. It just seemed common sense to go with the low dose radiation because it's such a simple process. Roland decided to do external beam radiotherapy. That's our primary modality of delivering radiation. And whenever somebody's getting radiation for prostate cancer, we talk about placing Barrigel spacer to help reduce rectal side effects. Doctor. Sundom explained to me that the Barrigel spacer is an injectable gel that's injected between your rectum and your prostate. Barrigel Spacer works by increasing the distance between the prostate and the rectum, allowing the radiation planner and the dosimetrists to deliver the radiation needed to the prostate while sparing the rectum and reducing rectal side effects after radiation. As a radiation oncologist, I'll actually see the patient through the radiation course. In general, we can really focus the radiation beams right on the target. But when you add the Barrigel spacer, that extra little bit can really help push the rectum out of that high dose area. After the Barrigel placed, it stays in place and it stays stable throughout the length of radiation. The gel itself will last through the radiation before it's absorbed by the body. It's a very safe material, hyaluronic acid, which has a very safe side effect profile. It was a quick, one time procedure. And after it was implanted, I left there, drove myself home, and never noticed it was there again. Roland, like most patients, had not ever heard of spacing in the treatment of radiation for prostate cancer. We'd been using spacers awhile, but when we first started using Barrigel, it was kinda like a light went off in our head. Finally, we could control the application of the gel to make sure that every patient had a symmetric response and had a good result that would help them with their radiation treatment. It's such a great procedure to help protect the rectum while also with the extra space I might be able to give some extra radiation which could actually lead to better cancer control, better outcomes. Sometimes I'll even talk with my urologist like, Hey, we're trying to give more radiation on this side of the prostate, so could you give a little bit more barrigel rectal spacer in this area to create more space to kind of allow the plan to be even better? We can really customize it for the patient, for their plan of care. The radiation part lasted forty five days. It was a very smooth process all the way through for me. No issues of any kind. I had zero rectal side effects of any kind. When you've taken the patients from their first steps of an elevated PSA through treatment, it's pretty fulfilling to see them going about their normal life and saying, I'm pretty much back to normal. I can definitely sleep easier at night knowing that we've done everything we can to really minimize their risk of long term rectal side effects. Barrigel Rectal Spacer allows the patient and the doctor to feel better about that. After the radiation was done, I felt free. You just go about your life, you know, do what you were doing prior to having the cancer.
Hear from Roland about his experience with Barrigel spacer during his prostate cancer radiation therapy.
Barrigel™Rectal Spacer is CLINICALLY PROVEN to reduce rectal side effects of prostate cancer radiation.1
Placed between the prostate and rectum before radiation therapy starts, the body-safe gel can be sculpted to fit the unique contours of your anatomy.1,4,5,8
“It was great. I had no problems. I feel that it gave me an added layer of protection because I have had no bowel problems. Talk with your doctor and make sure it is right for you. I highly recommend it.”†
Crispin
Real Barrigel™ Rectal Spacer Patient
“It was great. I had no problems. I feel that it gave me an added layer of protection because I have had no bowel problems. Talk with your doctor and make sure it is right for you. I highly recommend it.”†
Crispin
Real Barrigel™ Rectal Spacer Patient
"It was a very smooth process all the way through for me. No issues of any kind, and I had zero rectal side effects of any kind."
Ronald
Real Barrigel™ Rectal Spacer Patient
SAFETY and STABILITY.1,8
Barrigel™ spacer is the first and only hyaluronic acid rectal spacer.1,2,6 Made from a highly compatible, natural substance, the gel implant is designed to provide protection throughout the duration of your radiation therapy.1
The procedure is similar to your prostate biopsy and may be performed under local or general anesthesia—it can be performed in hospitals, outpatient clinics, or doctors' offices prior to the start of radiation treatment.

Barrigel™ rectal spacer is intended to temporarily position the anterior rectal wall away from the prostate during radiotherapy for prostate cancer and, in creating this space, it is the intent of Barrigel™ rectal spacer to reduce the radiation dose delivered to the anterior rectum. Barrigel™ rectal spacer is composed of biodegradable material and maintains space for the entire course of prostate radiotherapy treatment and is intended to be absorbed by the patient’s body over time. Barrigel™ rectal spacer should only be administered by qualified and properly trained physicians with experience in ultrasound guidance and injection techniques in the urogenital/pelvic area. As with any medical treatment, there are some risks involved with the use of Barrigel™ rectal spacer. Potential complications associated with the use of Barrigel™ rectal spacer include, but are not limited to: pain associated with Barrigel™ rectal spacer injection; needle penetration of the bladder, prostate, rectal wall, rectum, or urethra; injection of Barrigel™ rectal spacer into the bladder, prostate, rectal wall, rectum, urethra, or intravascularly; local inflammatory reactions; infection; urinary retention; rectal mucosal damage, ulcers, necrosis; bleeding; constipation; and rectal urgency. More information on indications, contraindications, warnings and instructions for use can be found in the Instructions For Use at www.barrigel.com. Individual results may vary.
Caution: Federal (USA) law restricts this device to sale by or on the order of a physician.
1. Mariados NF, Orio PF III, King MT et al. JAMA Oncol (2023).*§
2. King MT, Svatos M, Orio PF III et al. Pract Radiat Oncol (2023).*§
3. American Cancer Society. https://www.cancer.org/cancer/types/prostate-cancer/treating/radiation-therapy.html
4. Williams J, Mc Millan K, Bolton D et al. J Med Imag and Radiat Sci (2022).
5. Gejerman G, Goldstein MM, Chao M et al. Pract Radiat Oncol (2023).§
6. Data on File. As of 7/1/2025.
7. Barrigel Injectable Gel Instructions for Use (2022).
8. Svatos M, Chell E, Low DA et al. Med Phys (2024).*
*Study sponsored by Palette Life Sciences, now part of Teleflex.
§One or more authors have/had a financial relationship with Teleflex.
† As with any medical procedure, individual results may vary. See patient safety for more information.
Barrigel and the Barrigel logo are trademarks or registered trademarks of Teleflex Incorporated or its affiliates, in the U.S. and/or other countries.

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