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Safe spacing that puts you in control1-4

With Barrigel rectal spacer you have control to adapt to each patient’s unique anatomy.1-4 The result? Consistent coverage that supports safe outcomes.4,5 

Learn About Barrigel™ Rectal Spacer Frame

 

Help preserve your patients' bowel quality of life

Rectal side effects from prostate cancer radiation therapy can include7:

Radiation proctitis

Diarrhea


Rectal pain and bleeding

Barrigel™ rectal spacer is proven superior in the reduction of acute grade 2+ GI toxicity compared to control.1

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Without Spacer
Acute G2+ Toxicity Rate8-10:

10-38%

Depending on fractionation scheme

Barrigel Pivotal Trial
Acute G2+ Toxicity Rate1:

Barrigel™spacer cohort 2.9% 
Control cohort 13.8%

Hypofractionated regimen: 60Gy in 20 fractions (3Gy/Fx)

Acute toxicities have been shown to predict a higher rate of late toxicities11-12

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Results my vary

With Barrigel™ rectal spacer, YOU are in control.1-4

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Customize implant with sculptable gel to enable optimal coverage.1,2,4

Procedure time set by you, allowing you to pause and perform safety checks throughout the procedure.1,4

Highly visible on TRUS.1-4 Image-guided procedure allows you to refine or redirect placement.3,4

Achieve greater apical spacing for improved rectal dosimetry and better short-term bowel quality of life after radiation therapy.5

Space complex anatomy6

Learn more about Barrigel™ rectal spacer. Connect with your local Territory Manager for information and product demonstrations as you evaluate whether Barrigel spacer is right for your practice.

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Get More Information

Hear From Barrigel-Trained Physicians

“The ease-of-use injecting Barrigel™ rectal spacer allows the implanter to inject the spacer under no time constraint, and switch easily from sagittal to transverse ultrasound views for symmetrical, excellent coverage of the entire prostate gland. IT'S A NO BRAINER. ”

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Zachary Klaassen, MD, MSc†
Urologic Oncologist at Georgia Cancer Center

“My practice began using Barrigel™ spacer because it allows me to take the time necessary to create a symmetric implant that allows for protection of the entire rectum. Whether my patient is receiving IMRT, SBRT, or brachytherapy, Barrigel™ spacer allows me to PROTECT HEALTHY TISSUE from unwanted radiation exposure and reduce side effects.”

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Suraj_Singh

Suraj Singh, MD†
Radiation Oncologist Director at Parkview Comprehensive Cancer Center

Control matters for improved symmetry.

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BARRIGEL

Sculptable control over implant placement results in more symmetric coverage over the whole posterior rectal/prostate interface.

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Implant Symmetry RESULTS6

>95%

Pivotal Trial Patients; % of implants centered on prostate midline

PEG HYDROGEL

Lack of control over placement of the implant can result uneven and inconsistent coverage.

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Implant Symmetry RESULTS7

49%

Pivotal Trial Patients; % of implants centered on prostate midline

Rectal spacer properties.

Information provided for educational purposes only. No head-to-head study has been performed. Results from different clinical studies are not directly comparable.

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Barrigel Landing Page Rectal Spacer Properties Chart

Hear from Barrigel Physicians

“In my experience, Barrigel is safer due to the ability to control its location and alter its placement during the procedure. This allows us to have a MORE UNIFORM RESULT in tougher cases where another procedure could result in delay of care.”

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Varun Sundaram, MD
Urologist at Urology Austin in Austin, TX, and Designated Barrigel Center of Excellence

“The ease-of-use injecting Barrigel allows the implanter to inject the spacer under no time constraint, and switch easily from sagittal to transverse ultrasound views for symmetrical, excellent coverage of the entire prostate gland. IT'S A NO BRAINER. ”

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Zachary Klaassen, MD, MSc
Urologic Oncologist at Georgia Cancer Center

Resources for Physicians and Staff

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Explore clinical articles, educational videos, downloadable resources, event information and more.

Physician & Office Staff Resources
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Educational Videos
Procedural videos | On-demand webinars

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Barrigel Procedural Images
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Contact us today for more information about Barrigel™ Rectal Spacer

†Drs Klaassen and Singh are paid consultants of Teleflex.

1. Mariados NF, Orio PF III, King MT et al. JAMA Oncol (2023).*§
2. Svatos M, Chell E, Low DA et al. Med Phys (2024).*§ 
3. Williams J, Mc Millan K, Chao M et al. J Med Imag Radiat Sci (2022).§ 
4. Gejerman G, Goldstein MM, Chao M et al. Pract Radiat Oncol (2023).§ 
5. King MT, Svatos M, Orio PF III et al. Pract Radiat Oncol (2023).*§ 
6. McLean L, et al. Abstract #3236. Presented at ASTRO 2024 October 1, 2024.* 
7. National Cancer Institute. Radiation Proctisis. https://www.cancer.gov/about-cancer/treatment/side-effects/radiation-proctitis 
8. Rodda S, Tyldesley S, Morris JW et al. ASCENDE-RT: J Radiat Oncol Biol Phys. 2017;98(2):286-295.  
9. Dearnaley D, Syndikus I, Mossop H et al. Lancet Oncol. 2016;17:1047–60.  
10. Brand DH, Tree AC, Ostler P et al. Lancet Oncol. 2019; 20:1-13. 
11. Michalski JM et al. Int J Radiat Oncol Biol Phys (2010). 
12. Vargas C et al. Int J Radiat Oncol Biol Phys (2005). 

*Study sponsored by Teleflex.
§One or more authors have/had a financial relationship with Teleflex. 

Barrigel™ rectal spacer is intended to temporarily position the anterior rectal wall away from the prostate during radiotherapy for prostate cancer and, in creating this space, the intent is to reduce the radiation dose delivered to the anterior rectum. It is composed of biodegradable material and maintains space for the entire course of prostate radiotherapy treatment and is intended to be absorbed by the patient’s body over time.
It should only be administered by qualified and properly trained physicians with experience in ultrasound guidance and injection techniques in the urogenital/pelvic area.

Potential complications include but are not limited to: pain associated with the injection; needle penetration or injection of Barrigel rectal spacer into the bladder, prostate, rectal wall, rectum, urethra, or intravascularly; local inflammatory reactions; infection; urinary retention; rectal mucosal damage, ulcers, necrosis; bleeding; constipation; and rectal urgency. Contraindicated in prostate cancer patients with clinical stage T4 disease. Individual results may vary. Visit barrigel.com

Caution: Federal (USA) law restricts this device to sale by or on the order of a physician.

Barrigel and the Barrigel logo are trademarks or registered trademarks of Teleflex Incorporated or its affiliates, in the U.S. and/or other countries.

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